Xinbin Chen, Ph.D. for UC Davis Health

Xinbin Chen, Ph.D.

Professor

Reviews

Specialties

Hematology/Oncology

Department

Internal Medicine

Locations and Contact

Tupper Hall

Tupper Hall- UC Davis

Davis, CA 95616

Get Directions

Additional Numbers

Clinic Phone

530-754-8404

Physician Referrals

800-4-UCDAVIS (800-482-3284)

Division

Hematology and Oncology

Center/Program Affiliation

UC Davis Comprehensive Cancer Center

Undergraduate School

B.S. (D.V.M.), Veterinary Medicine, Anhui Agricultural University, China 1982

Other School

M.S., Animal Sciences, Michigan State University, East Lansing MI 1987

Other School

Ph.D., Microbiology, Michigan State University, East Lansing MI 1991

Other School

M.S., Microbiology, Nanjing Agricultural University, China 1985

Distinguished Teaching Award for Graduate and Professional Teaching at UC Davis, 2022

Pfizer Animal Health Excellence in Research Award, UC Davis School of Veterinary Medicine, 2010

NIH First Award (R29) to New Investigator, 1997, 1998, 1999, 2000, 2001

Faculty Career Development Award, Department of Defense Breast Cancer Research Program, 1997, 1998, 1999, 2000, 2001

Distinguished Teaching Award, School of Graduate Studies, Medical College of Georgia (now Georgia Health Sciences University), 2000

Kong X, Wang D, Sun W, Chen M, Chen J, Shi J, Zhang J, Chen X. Small Proline-Rich Protein 2A and 2D Are Regulated by the RBM38-p73 Axis and Associated with p73-Dependent Suppression of Chronic Inflammation. Cancers (Basel). 2021 Jun 6;13(11):2829. doi:10.3390/cancers13112829. PMID:34204113.

Sun W, Laubach K, Lucchessi C, Zhang Y, Chen M, Zhang J, Chen X. Fine-tuning p53 activity by modulating the interaction between eukaryotic translation initiation factor eIF4E and RNA-binding protein RBM38. Genes Dev. 2021 Apr 1;35(7-8):542-555. doi:10.1101/gad.346148.120. Epub 2021 Mar 4. PMID:33664057.

Lucchesi CA, Zhang J, Ma B, Nussinov R, Chen X. Survivin Expression Is Differentially Regulated by a Selective Cross-talk between RBM38 and miRNAs let-7b or miR-203a. Cancer Res. 2021 Apr 1;81(7):1827-1839. doi:10.1158/0008-5472.CAN-20-3157. Epub 2021 Jan 20. PMID:33472892.

Mohibi S, Zhang J, Chen X. PABPN1, a Target of p63, Modulates Keratinocyte Differentiation through Regulation of p63α mRNA Translation. J Invest Dermatol. 2020 Nov;140(11):2166-2177.e6. doi:10.1016/j.jid.2020.03.942. Epub 2020 Mar 31. PMID:32243883.

Zhang Y, Feng X, Zhang J, Chen X. Iron Regulatory Protein 2 Exerts its Oncogenic Activities by Suppressing TAp63 Expression. Mol Cancer Res. 2020 Jul;18(7):1039-1049. doi:10.1158/1541-7786.MCR-19-1104. Epub 2020 Apr 10. PMID:32276991.

Zhang J, Kong X, Zhang Y, Sun W, Wang J, Chen M, Chen X. FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression. J Pathol. 2020 Jul;251(3):284-296. doi:10.1002/path.5451. Epub 2020 May 18. PMID:32304229.

Zhang J, Kong X, Zhang Y, Sun W, Xu E, Chen X. Mdm2 is a target and mediator of IRP2 in cell growth control. FASEB J. 2020 Feb;34(2):2301-2311. doi:10.1096/fj.201902278RR. Epub 2019 Dec 12. PMID:31907996.

Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nat Commun. 2019 Oct 11;10(1):4621. doi:10.1038/s41467-019-12529-3. PMID:31604910.

Zhang J, Sun W, Kong X, Zhang Y, Yang HJ, Ren C, Jiang Y, Chen M, Chen X. Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24259-24267. doi:10.1073/pnas.1913919116. Epub 2019 Nov 11. PMID:31712410.

Zhang Y, Feng X, Zhang J, Chen M, Huang E, Chen X^. Iron regulatory protein 2 is a suppressor of mutant p53 in tumorigenesis. Oncogene. 2019 Jul 22;38(35):6256-6269. doi:10.1038/s41388-019-0876-5.