Jiejun (Jeff) Wu, M.D., Ph.D.

Resident, PGY-4

Medical School:
Hebei Medical University

Personal Interests:
Chinese calligraphy; outdoor and social activities including hiking, running, and community volunteering.

Reason for selecting UC Davis for Residency:
Dedicated faculty, friendly atmosphere, many training opportunities, and great location full of sunshine.

Clinical Interests

• Surgical Pathology
• Clinical Pathology

Research Interests

• Clinical and Translation Research

CV Highlights/Brief Biography:

Dr. Wu earned his medical degree from Hebei Medical University and his PhD in molecular genetics from Ohio State University. Afterword, he has executed multiple research projects in both industry and academia before joining UC Davis to pursue his career goal in pathology.

Publications, Abstracts and/or Posters

* These authors contributed equally to this work.

Ozer HG, Huang YW, Wu J, Parvin JD, Huang TH, Huang K. "Comparing Multiple ChIP-sequencing Experiments". J Bioinform Comput Biol. 2011 Apr;9(2):269-82.

Sun H*, Wu J*, Wickramasinghe P*, Pal S*, Gupta R*, Bhattacharyya A, Agosto-Perez FJ, Showe LC, Huang TH, Davuluri RV. "Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq". Nucleic Acids Res. 2011 Jan 1;39(1):190-201.

Gu F, Hsu HK, Hsu PY, Wu J, Ma Y, Parvin J, Huang TH, Jin VX. "Inference of hierarchical regulatory network of estrogen-dependent breast cancer through ChIP-based data". BMC Syst Biol. 2010 Dec 17;4:170.

Ozer HG, Wu J, Huang YW, Parvin J, Huang T, Huang K. "Comparing Multiple Protein Binding Profiles in ChIP-seq Experiments". Proc. of CSB. 2010 Aug; 9:92-9.

Liu Z*, Wu J*,  Xie Z, Liu S, Fan-Havard P, Huang TH, Plass C, Marcucci G, Chan KK. "Quantification of regional DNA methylation by liquid chromatography /tandem mass spectrometry". Anal Biochem. 2009 Aug 15;391(2):106-13. Epub 2009 May 12.

Taslim C, Wu J, Yan P, Singer G, Parvin J, Huang T, Lin S, Huang K. "Comparative Study on ChIP-seq Data: Normalization and Binding Pattern Characterization". Bioinformatics. 2009 Sep 15;25(18):2334-40. Epub 2009 Jun 26.

Liu Z, Xie Z, Liu S, Pavlovicz RE, Wu J, Plass C, Li PK, Li C, Huang TH, Marcucci G, Chan KK. "Modulation of DNA methylation by a sesquiterpene lactone parthenolide". J Pharmacol Exp Ther. 2009 May;329(2):505-14.

Ozer HG, Bozdag D, Wu J, Camerlengo T, Huang YW, Hartley T, Parvin J, Huang T, Catalyurek U, Huang K. "A Comprehensive Analysis Workflow for Genome-Wide Screening Data from ChIP-Sequencing Experiments". Proc. of BICoB. 2009 Apr; 5462: 320-30.

Feng W, Liu Y, Wu J, Nephew KP, Huang TH, Li L. "A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology". BMC Genomics. 2008 Sep 16;9 Suppl 2:S23.

Wu J, Huang TH. "ChIP-chip meets nutrition: probing genome-wide dietary effects". Nutr Rev. 2008 Aug;66 Suppl 1:S49-53

Singer GA*, Wu J*, Yan P, Plass C, Huang TH, Davuluri RV. "Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling array". BMC Genomics 2008, 9:349.

Wu J, Wang SH, Potter D, Liu JC, Smith LT, Wu YZ, Huang TH, Plass C. "Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing". BMC Genomics. 2007 May 24;8:131.

Wu J, Smith LT, Plass C, Huang TH. "ChIP-chip comes of age for genome-wide functional analysis". Cancer Res. 2006 Jul 15; 66(14):6899-902.

Yang, H, Duan, D, Wu, J, Zhao, C, Cai, Q, Xu, Q. "Ex vivo expression of TH and GDNF genes with retrovirus vector". Chinese Journal of Neuroanatomy. 2004 20:3, 215-219.

Abstracts and Conference Presentations

He G, Yan M, Wu Q, Wang Y, Zhang Y, Lu JA, Wu J, Li X, Zhao S, Gu P, Iqbal J, Zhang YH. "Experience and impacts of remote telepathology consultation in improving cancer patients’ diagnosis and management in China". Journal of Clinical Oncology. 2019 37:15 (suppl), e18337

Huang K, Wu J, Zhang J, Huang T, Parvin J. "GenomeScape: a universal 3D visualization tool for genomic data", AMIA Annual Summit on Translational Bioinformatics, San Francisco, March 2009.

Wu J, Liu Y, Wang X, Nephew KP, Yan P, Li L, Huang TH. "Whole-genome characterization of estrogen-regulatory elements in breast cancer cells by massive parallel sequencing". National Cancer Institute-Integrative Cancer Biology Program Steering Committee Meeting, Columbus OH, May 2008

Wu J, Huang K, Liu Y, Huang, YW, Jin V, Wang X, Nephew KP, Yan P, Li L, Huang TH. "Whole-genome characterization of estrogen-regulatory elements in breast cancer cells by massive parallel sequencing". 7th Annual OSUMC Research Day, Columbus OH, April 2008.

Wu J, Liu Y, Wang X, Nephew KP, Yan P, Li L, Huang TH. "Whole-genome characterization of estrogen-regulatory elements in breast cancer cells by massive parallel sequencing". 2008 AACR Annual Meeting, San Diego, CA, March 2008.

Liu Z, Wu J, Xie Z, Liu S, Aimiuwu EJ, Plass C, Huang TH, Marcucci G, Chan KK. "A specific and sensitive LC-MS/MS method for accurate quantification of gene specific methylation (GSM)". 2007 AAPS Annual Meeting & Exposition, San Deigo, CA, November 2007.

Wu J, Singer GA,  Davuluri RV, Huang TH. "Combination of whole-genome parallel sequencing and Chromatin immunoprecipitation in characterization of  mammalian promoter usage". 2007 MBCG Bi-Annual Research Retreat, Perrysville, OH, November 2007.

Wu J, Huang TH, Plass C. "Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing". 9th Annual Comprehensive Cancer Center Scientific Meeting, Columbus, OH, February 2007.

Wu J, Huang TH, Plass C. "The diverse status of histone modifications in relation to DNA methylation in mouse leukemia cell line identified by ChIP-chip and RLGS". 2006 Scott Falkenthal Memorial Colloquium, Columbus, OH, April 2006.

Wu J, Huang TH, Plass C. "The diverse status of histone modifications in relation to DNA methylation in mouse leukemia cell line identified by ChIP-chip and RLGS". 8th Annual Comprehensive Cancer Center Scientific Meeting, Worthington, OH, February 2006.